Center For AIDS Research

March 31 - April 7, 2015

The Network News
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March 31 - April 7, 2015
Divider RuleResearch Factoid of the Day ...

Valacyclovir, which is commonly used to control HSV-2 (think: genital herpes), appears to reduce the levels of HIV in people; possibly by interfering with HIV's ability to reproduce.

"This study builds on our earlier published work on the impact of acyclovir on HIV-1. Because of the success of this study, [we] plan to conduct larger, randomized trials with the hope that valacylovir can eventually be added to the drug cocktail used to treat HIV."
-Raymond Schinazi

Read the Emory News article

Divider Rule Kudos ...
     Hope Clinic

... to the Hope Clinic for having been selected by the Atlanta Freedom Bands (AFB) as a Heroic Organization honoree. At their "Heroes and Heroines" concert on March 21, the AFB Concert Band dedicated the piece "With Visions of Tomorrow," by composer Brant Karrick, to Hope Clinic faculty, staff, and volunteers. As stated in the announcement letter: "The composer wrote the piece as a celebration of breakthroughs in the sciences, arts, and industry that improve the human condition. We think this is a perfect theme to celebrate the work that everyone in the Hope Clinic does that promises to save lives and cure diseases around the world."
Listen to "With Visions of Tomorrow" here (07:02).

...and to two talented researchers on scoring their first ever NIH funding. Hurrah for
Charlene Wang
(F31) and Steven Bosinger (R21)!!

     Charlene Wang

We know that CCR5 is the main coreceptor used for HIV entry into target cells and that people with a mutation that prevents cell surface expression of CCR5 may be functionally immune to HIV. MMG graduate student Charlene Wang seeks to build a foundation for interpreting the results of eradication therapies that are being designed to artifically suppress CCR5 expression by elucidating the mechanisms through which CCR5 modulates HIV replication and viremia.
Read more about Mechanisms for Decreased HIV Transcription in CCR5 Delta-32 Heterozygotes on ART (1F31AI118558-01).

Steven Bosinger     

Despite being on ART, people with HIV continue to suffer inflammation (which is a bad thing). Steven Bosinger, Co-Director of the Yerkes Nonhuman Primate Genomics Core Lab, aims to begin cracking the code on why residual inflammation happens by engaging in monkey business with a novel reagent that specifically depletes plasmacytoid dendritic cells (pDCs) to test the hypothesis that pDCs drive disease-related inflammation in SIV-infected monkeys.
Read more about Experimental Depletion of Plasmacytoid Dendritic Cells in SIV Infection (1R21AI118542-01).

Welcome to the Show Charlene and Steven!

Divider Rule In other news...

Happy Birthday

... to Paula Frew (April 1)

We hope that your birthday is as much fun as you are ... but that sets a very high standard!


     SIV PET scan

Quick ... how was this picture taken and who is of? If you guessed a whole body PET scan of a live rhesus macaque who displays a startlingly high level of SIV in his sinus cavities you are either a REALLY good guesser or you already read the trés interesting articles in Science Magazine and Nature Methods. Want to know more about the pinpoint SIV-finding method Francois Villinger and his all star team of CFAR scientists adapted from cancer medicine? The see-it-to-believe-it findings they unearthed? Some icy hot possible future uses of the technique in HIV-infected homo sapiens? Why David Margoles counsels data use caution?
Read More About It

Divider Rule Bulletin Board...

bulletin board

Survey Participants Wanted: HIV Care Providers
This study attempts to characterize the patient-provider encounters pertaining to alcohol and substance use from the point of view of HIV care providers. Eligible study participants include physicians, physician assistants, nurse practitioners, and pharmacists. The study consists of one anonymous online survey which will take about 15-20 minutes to complete. After completing the online survey, participants will have the option of participating in a gift card lottery (5 amazon.com gift cards will be randomly drawn, each worth $100).
Interested? Contact Sarahmona Przybyla, PhD, MPH; Research Institute on Addictions, SUNY at Buffalo. sprzybyla@ria.buffalo.edu


Divider Rule Government News...

Government News

     CDC

The CDC has released two reports presenting HIV prevalence and risk behaviors data among injecting drug users. The MMWR report presents weighted data on HIV prevalence and key IDU behaviors in 20 cities (including Atlanta). The DHAP Surveillance Report provides descriptive, unweighted data on HIV risk behaviors by three infection categories: HIV-negative, HIV-positive-aware (IDUs who are aware of their HIV infection), and HIV-positive-unaware (IDUs who are not aware of their HIV infection).


NIH     

Struggling with your new NIH Biosketch version C? YOU ARE NOT ALONE. Start getting a grip by downloading this easy reading RSPH Grand Rounds slide set by Gary Miller and Janet Gross. It is chockful of really helpful hints AND completely validates why you are so upset about the new form.
Also, would a cheat sheet be helpful? Check out an NIH-generated sample example.

... And speaking of updated forms, NIH recently announced that the use of the updated Inclusion Enrollment format is now required when submitting progress reports.
Read the Notice

Divider Rule Focus On... 2015 NIH CFAR Supplement Request

     Focus On...

The 2015-2016 NIH CFAR supplement request has just been released.
Click here to view / download the FOA

This year the NIH CFAR is interested in supplement applications in the following scientific areas:

  1. Advancing PrEP Delivery
  2. HIV Transmission and Microepidemics
  3. Projects that Highlight the Value Added from Inter-CFAR collaborations
  4. Glycomics in HIV Co-Morbidities

If you are interested in submitting an application in any of the areas listed above please send:

  1. An initial email to the CFAR Developmental Core (cfar@emory.edu), indicating interest.
  2. A 1-page pre-proposal to the Developmental Core by Monday, April 20 for competitive review by the CFAR Co-Directors later that week.

The key aspects of this funding opportunity are:

  • NIH Deadline: May 22, 2015
  • Budget: $100,000 in direct costs
  • Project Period: One year
  • Allowable Project Directors:
            • Early stage investigators who are R01 eligible
            • Investigators in non-HIV fields who have never received an R01 in HIV/AIDS
            • Post-docs are NOT eligible for this announcement
  • Application limit: One per CFAR per scientific area of interest
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Research

Request for Information

April 10 (deadline)
Sponsor: NIH/NIMHD
NOT-DA-15-052
Availability of Data and Biological Specimens from NIH-funded Studies of HIV and Non-HIV-Infected Injection Drug Users for Genetic and Epigenetic Analyses


Funding Opps

STANDARD AIDS DATES

Sponsor: NINR, OBSSR
R01
R21
Functional Wellness in HIV: Maximizing the Treatment Cascade

OTHER

May 15 (App)
Sponsor: Multiple Institutes
Admin Supplement
Administrative Supplements for Research on HIV/AIDS and Aging

July 19 (LOI)
Sponsor: NIMH, NIAID
R01
R21
Methodologies to Enhance Understanding of HIV-Associated Social Determinants

August 2 (LOI)
Sponsor: NIMH, NINDS
R01
R21
The Role of Exosomes in HIV Neuropathogenesis

September 2 (App)
Sponsor: NIDA
R03
AIDS-Science Track Award for Research Transition

PREVIOUS LISTINGS:
ALL

See previously advertised Funding Opportunities in Network News archived issues.

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Calendar Upcoming Events
 
April 1
6:00pm
VDC Dinner & A Movie Night
Dr. Ehrlich's Magic Bullet (1940)
Starring: Edward G. Robinson
Register here

April 2
8:00am
ID Seminar
Daptomycin Resistance: Mirror into Host Defense
Starring: Arnold Bayer, MD
     Associate Chief, Adult Infectious Diseases
     Geffen School of Medicine at UCLA
     Senior Investigator, LA Biomedical Institute
Location: RSPH / GCR / Rita Anne Rollins Room

April 2
10:00
Dissertation Defense
Why should I put myself at risk of HIV for something that is useless?
Abstract: Emic understandings and structural correlates of risky transactional sex in Swaziland
Starring: Rebecca Fielding Miller
Location: RSPH/CNR/3001

Calendar Farther Down the Road
April 6 (Abstract Deadline)
December 6-9 (Conference)
2015 HIV Prevention Conference
Accelerating Progress
Location: Hyatt Regency & Marriott Marquis; Atlanta
Website
Abstract Submission Information

April 13-15, 2015
8:00 - 3:50pm
Conference
2015 Annual Conference on Vaccine Research
Location: Bethesda
Website
Agenda

May 18-21
50th Annual USPHS Scientific and Training Symposium
Public Health Diversity: Succeeding in a Flatter World
Location: Sheraton Atlanta
Website

October 5 (Abstract Deadline)
December 6-10 (Conference)
HEP DART 2015
Frontiers in Drug Development for Viral Hepatitis
Location: Wailea, Maui, Hawaii
Website
Abstract Submission Information

October 28-30: Save the Date
SNSRN 2015
Integrating Social, Behavioral, and Biomedical Strategies: The Future of HIV/AIDS Prevention and Care Research
Host: Johns Hopkins University CFAR
Location: Baltimore

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Spotlight Spotlight

Footlights | Vaccine Dinner Club - Wednesday, April 1

     VDC logo

 

Count Me In!
Click Here to Register

'Dinner & a Movie Night'
Dr. Ehrlich's Magic Bullet
(1940)

Starring

Dr. Paul Ehrlich (Edgar G. Robinson)
Mrs. Hedy Ehrlich (Ruth Gordon)
Dr. Emil von Behring (Otto Kruger)

Plus a Cast of Thousands with Diphtheria and Syphilis
(but not necessraily at the same time)

From the back of the film box:

"Edward G. Robinson gives a powerful and moving performance in this compelling film that documents one doctor's valiant struggle to make medical history."

"Medical maverick Dr. Paul Ehrlich (Robinson) risks everything -- including his life -- when, in his quest to discover a simple diagnosis for tuberculosis, he inadvertently develops the deadly disease himself. Traveling to Egypt with his wife (Ruth Gordon) in search of a cure, he stumbles on a theory of poison immunity, with which he hopes to eradicate diphtheria and syphilis -- the major killers of the time. But putting his theories to practice back in Germany is no easy task: the good doctor must brave prejudice, fascism, sickness and even financial ruin in order to actualize his vision and discover the building blocks of modern medicine."

"Directed by William Dierterle (The Life of Emile Zola) and written by John Huston (director of The Maltese Falcoln and The Afrcian Queen), Dr. Erlich's Magic Bullet was one of the most daring films of its time, controversial and challenging in its subject and style. Today's audiences are sure to find its suspense and drama both thrilling and captivating."

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CFAR logo

The Network News is a periodic email, detailing HIV/AIDS related events, funding opportunities, and achievements of CFAR members. If you have items that you wish to have included, please send them to us at cfar@emory.edu by Friday of each week. Please put "The Network News" in the subject line.

The Network News is distributed to CFAR members and fans by email every Monday. Except when it isn't.

Editor, Kimberley (Kimbi) Sessions Hagen, EdD

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Emory University Center for AIDS Research Emory University Center for AIDS Research