Center For AIDS Research

September 8-15, 2015

The Network News
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September 8-15, 2015
Divider Rule Quote of the Week ...

This week's quotes are dedicated to Wendy Armstrong, Melanie Thompson, and Jeff Graham. See Government News.

Each time someone stands up for an ideal, or acts to improve the lot of others, or strikes out against injustice, they send forth a ripple of hope...
(John F. Kennedy)

Ripples grow up to be rivers.
(Traditional)

Divider Rule Kudos ...
     Ann Chahroudi

... to Ann Chahroudi on scoring her first NIH funding!

"To disrupt" means to stop an ongoing event, activity, or process -- think: email (USPS) and Uber (taxis). Ann wants to apply some of that disruption mojo to CD4+ T-memory stem cells (TMSC); the Peter Pan cells of your immune system (they want to live forever, without ever growing up) in order to stop them from self-renewing and, therefore, acting as exceptionally long lived HIV reservoirs. Ann's project (R56AI117851) will test a novel therapeutic approach that will, hopefully, force CD4+ TM stem cells to stop drinking from the Fountain of Youth.
(Targeting Beta-Catenin to Disrupt the T Memory Stem Cell Reservoir)

Red Ribbon     

... and to CFARians in the Division of Infectious Diseases for snagging 50% of all Department of Medicine faculty research awards announced this past June [while Network News was on hiatus]. These include:

• Carlos del Rio:
    R. Wayne Alexander Excellence in Research Accomplishment
• Marshall Lyon:
    Outstanding Scientific Citation, Senior Clinical Faculty
• Jyothi Rengarajan:
    Outstanding Scientific Citation, Junior Basic Science Faculty
Divider Rule In other news...

Happy Birthday

... to Lilin Lai (September 8), Teresa Parker (September 9), Frank McDonald (September 10), Eileen Burd (September 11), Safiya George-Dalmida (September 13), and Dick Compans (September 15)

Another year, another fabulous excuse for eating cake.


     Money Tree

Want to crowdfund your research? Emory has opened a "Momentum" website to match donors with causes that matter to them. Think of projects in the $5,000 to $15,000 range that will catch the public's fancy ... you'll have 30 days to meet your funding goal.
Apply Here.

 

Mehul Suthar     

And speaking of project ideas, Mehul Suthar came up with one that caught NIH's fancy; he has been awarded R21 funding (R21AI113485) to use some of those new-fangled "Collaborative Cross" mice to examine the degree to which host genetics affects the ability of dendritic cells to recognize a harmful virus (e.g. HIV) when one tries to sneak by. Reminder: dendritic cells are the police / paddy wagons of your immune system -- it is their job to stop and frisk bad bugs that have breached your skin/mucosal defenses and then cart them off to the nearest T-cell for a speedy trial and execution.
(Identifying Host Genetic Determinants That Regulate Dendritic Cell Activation)

Divider Rule Bulletin Board...

bulletin board

Female Volunteers Wanted: Hormonal Contraceptives and HIV Prevention
Emory Student Health Services and the CDC are conducting a study to establish salivary estrogen-progesterone levels in women who are using either:
• NuvaRing
• Oral or injectable contraceptives
• Mirena or ParaGuard IUD
• Condoms or other barrier methods
• No birth control

The results will guide development of HIV prevention studies investigating vaginal rings that release both HIV pre-exposure prophylaxis drugs and hormonal contraceptives.
For more information contact: emoryshcs.nuvaringstudy@gmail.com

Divider Rule Government News...

Government News

     CDC

This item actually belongs in the KUDOS section because the leadership of the Georgia Medicaid Office deserve some seriously excellent recognition and thanks for being willing to change their mind!

BACK STORY: The Medicaid office had been planning to restrict access to three, single tablet antiretroviral regimens (Stribild®, Triumeq®, and Complera®) favored by the DHHS ARV Guidelines. Restricting access wouldn't have made much medical sense (think: single tablet regimen = fewer pills = higher adherence = improved outcomes = lower hospitalization rates = lower health care costs = everybody wins!) particularly given that, in the case of Stribild®, some of the ARV component parts are not even available outside of the single tablet version. PLUS, restricted access would have meant that patients were required to 'fail' on other regimens before Medicaid would consider approving the desired drugs (think: worse drugs = time lost + side effects + increased drug resistance = everybody loses). All of this would have been a serious blow to our most financially vulnerable patients.

But the Medicaid Drug Utilization Review Board changed their mind and all three drugs will REMAIN on the preferred list. Hurrah!!

     Wendy Armstrong     Melanie Thompson     Jeff Graham
 
Wendy Armstrong
 
Melanie Thompson
 
Jeff Graham

This did NOT happen spontaneously. We all owe a huge debt to Wendy Armstrong and Melanie Thompson, who met with Linda Wiant and other Medicaid officials to build bridges and provide education -- and are now working to bring pharma to the table as well --, AND to Jeff Graham who spearheaded a grassroots petition campaign through the Georgia HIV Advocacy Network.
Hail to Our HIV Heroes!

Divider Rule Focus On...: CFAR Publications

Focus On...    
     pubs




CFARians have been busy, Busy, BUSY in the last year getting publications out the door and in print. Below are some of the publications citing the CFAR that would have appeared over the summer, had Network News not been on hiatus. More will appear next week

Dauria EF, Elifson K, Arriola KJ, Wingood G, Cooper HL. Male Incarceration Rates and Rates of Sexually Transmitted Infections: Results From a Longitudinal Analysis in a Southeastern US City. Sex Transm Dis. 2015 Jun;42(6):324-8. doi: 10.1097/OLQ.0000000000000268

Dilernia DA, Chien JT, Monaco DC, Brown MP, Ende Z, Deymier MJ, Yue L, Paxinos EE, Allen S, Tirado-Ramos A, Hunter E. Multiplexed highly-accurate DNA sequencing of closely-related HIV-1 variants using continuous long reads from single molecule, real-time sequencing. Nucleic Acids Res. 2015 Jun 22. pii: gkv630. 26101252

Mitchell JW, Sullivan PS. Brief Report: Relationship and Demographic Factors Associated With Willingness to Use an In-Home Rapid HIV Test to Screen Potential Sex Partners Among a US Sample of HIV-Negative and HIV-Discordant Male. J Acquir Immune Defic Syndr. 2015 Jun 1;69(2):252-6. doi: 10.1097/QAI.0000000000000594.

Cho JH, Coats SJ, Schinazi RF. Synthesis of carbocyclic nucleoside analogs with five-membered heterocyclic nucleobases. Tetrahedron Lett. 2015 Jun 3;56(23):3587-3590. PMCID: 26028788

Spaulding AC, MacGowan RJ, Copeland B, Shrestha RK, Bowden CJ, Kim MJ, Margolis A, Mustaafaa G, Reid LC, Heilpern KL, Shah BB. Costs of Rapid HIV Screening in an Urban Emergency Department and a Nearby County Jail in the Southeastern United States. PLoS One. 2015 Jun 8;10(6):e0128408. doi: 10.1371/journal.pone.0128408. eCollection 2015

Chowdhury A, Hayes TL, Bosinger SE, Lawson BO, Vanderford T, Schmitz JE, Paiardini M, Betts M, Chahroudi A, Estes JD, Silvestri G. Differential impact of in vivo CD8+ T-lymphocyte depletion in controller versus progressor SIV-infected macaques. J Virol. 2015 Jun 10. pii: JVI.00869-15. PMCID: 26063417

Divider Rule
Research

Funding Opps

STANDARD AIDS DEADLINES: (5/7, 9/7, 1/7)

Sponsor: Multiple NIH Inst.
R01
R03
R21
Multidisciplinary Studies of HIV/AIDS and Aging
Please let CFAR know if you plan to apply for one of these mechanisms

 

Sponsor: NIAID, NIMH
R21
Exploiting RNA as a Target for HIV Interventionsg

 

NON-STANDARD DEADLINES:

No May deadline
(Sept. and Jan. only)

Sponsor: NIAID, NCI, NIMH
R01
R21
Ethical Issues in Research on HIV/AIDS and its Co-Morbidities

 

January 15, 2016
Sponsor: NIMHD
U01
Behavioral Interventions to Prevent HIV in Diverse Adolescent Men Who Have Sex with Men

 

PREVIOUS LISTINGS:
ALL

See previously advertised Funding Opportunities in Network News archived issues.

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Calendar Upcoming Events

September 10
8:00am
ID Seminar
Mycobacterium tuberculosis immune evasion and evolution: Why is it hard to make a TB vaccine?
Starring: Joel Ernst, MD (NYU)
Location: RSPH / GCR / Rita Anne Rollins Room

September 10
11:30am - 1:30pm
Social Occasion
Faculty and Staff Lunch
As a means to foster casual and social interaction, collaboration and community, the Emory Faculty Club Planning Committee has arranged with the Emory Dining Office to establish a new program for faculty and staff to enjoy lunch together
Location: Winship Ballroom, the DUC
Cost: $7 plus tax, All you can eat
• Pay at register at top of spiral staircase


Calendar Farther Down the Road
September 16-17
Workshop
Bridging the Sciences Workshop 2015:
HIV, Chikungunya, Dengue, Ebola, Norovirus, Emerging Infections

Location: Hyatt Regency Pier Sixty-Six
    Fort Lauderdale, FL
Sponsors:
• Emory School of Medicine Dept. of Pediatrics
• CFAR at Emory University
• CFAR at the University of Miami
• Miami Clinical and Translational Science Institute
• US Dept. of Veteran's Affairs
• University of Miami Miller School of Medicine
Conference Website

September 17
12:00 - 1:00pm
Workshop
Research Resources 101: Learn about crowdfunding at Emory, a new avenue for research support
Location: Emory University Hospital Auditorium (2nd floor, E wing)
RSVP by September 16
Watch it remotely
See related article in "In Other News" section

September 17
5:30pm - 8:00pm
Pizza Party
CFAR 101: Everything You Should Know About the CFAR Can Help You, But Never Knew to Ask
See Spotlight section

September 20
3:00pm - 5:00pm
Celebration
2015 AV200 Check Presentation and Closing Party
Location: SOM
RSVP to Jane Lawson

October 5 (Abstract Deadline)
December 6-10 (Conference)
HEP DART 2015
Frontiers in Drug Development for Viral Hepatitis
Location: Wailea, Maui, Hawaii
Website
Abstract Submission Information

October 28-30
SBSRN 2015
Integrating Social, Behavioral, and Biomedical Strategies: The Future of HIV/AIDS Prevention and Care Research
Host: Johns Hopkins University CFAR
Location: Baltimore

October 29
November 5
11:30am - 1:30pm
Social Occasion
Faculty and Staff Lunch
As a means to foster casual and social interaction, collaboration and community, the Emory Faculty Club Planning Committee has arranged with the Emory Dining Office to establish a new program for faculty and staff to enjoy lunch together
Location: Winship Ballroom, the DUC
Cost: $7 plus tax, All you can eat
• Pay at register at top of spiral staircase

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Divider Rule
Spotlight Spotlight

Footlights | CFAR Network Pizza Party - Thursday, September 17

     Pizza Party logo

 

Count Me In!
Click Here to Register

 

CFAR 101:
Everything You Should to Know About What CFAR Can Do For You ...
But Never Knew to Ask

Starring

The CFAR Cores

Biostatistics
Developmental
Clinical Research
Prevention Science
Immunology
Virology

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CFAR logo

The Network News is a periodic email, detailing HIV/AIDS related events, funding opportunities, and achievements of CFAR members. If you have items that you wish to have included, please send them to us at cfar@emory.edu by Friday of each week. Please put "The Network News" in the subject line.

The Network News is distributed to CFAR members and fans by email every Tuesday. Except when it isn't.

Editor, Kimberley (Kimbi) Sessions Hagen, EdD

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