Center For AIDS Research

June 3, 2020

The Network News
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Please remember to cite the CFAR. Citing the CFAR grant number (AI050409) on all publications and presentations that benefited from any level of Emory CFAR consultation, services, materials, mentorship, or funding is crucial in ensuring our continued support from NIH.

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June 3, 2020
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Bill Mauldin

 
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Online solidarity vigil, June 5 at 4:00pm
to mourn the lives lost and lift our dream for an anti-racist world.

 
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Kudos ...

     Colleen Kraft     
     Colleen Kraft     
              

... to CFAR Virology and Molecular Biomarkers Core Associate Director Colleen Kraft on being selected by The Atlanta Business Chronicle as a Health Care Heroes 2020 winner in the Physician category.

Colleen was recognized for her ongoing work in serious communicable diseases (Ebola, Lassa, SARS-CoV-2).

Read More About It:
Emory News article

 
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In Other News ...

Congratulations to Rama Amara, Cindy Derdeyn, Eric Hunter, and Bali Pulendran, senior authors of a recent Nature Medicine article "T cell-inducing vaccine durably prevents mucosal SHIV infection even with lower neutralizing antibody titers.""

    
    
     Rama Amara      Cindy Derdeyn      Eric Hunter      Bali Pulendran     
     Rama Amara      Cindy Derdeyn      Eric Hunter      Bali Pulendran     
    

Your immune system has two major ways of stopping bad bugs in their tracks -- cell-mediated immunity and antibody-mediated immunity.

Think of the difference between them as either hiring a ninja warrior to kill a bad guy in hand-to-hand combat (cell-mediated immunity) or releasing attack dogs who completely immobilize it (antibody-mediated immunity).

Most HIV vaccine candidates stimulate antibodies (attack dogs) but a vaccine developed at the EVC adds a new twist: a gene for a viral protein that stimulates cellular immunity (ninja warriors).

In the experiment, which was partially supported by the CFAR, one group of rhesus macaques received several doses of "Env," a viral protein that stimulates antibody production; a second group received the same series plus a gene for "Gag," a viral protein that stimulates cellular immunity. A third group served as a control.

Five months after receiving the vaccine doses, four out of six animals that were exposed to Env+Gag (attack dog + ninja warrior) remained free of infection, compared to only one animal that was exposed to Env (attack dog) alone. AND the added protection provided by Env+Gag lasted longer (up to a year so far).

Extra added bonus... early indications are that the same approach might be feasible for other bad bugs, including influenza, TB, malaria and SARS-CoV-2. Wowser!!

Read More About It
Emory News article
Nature Medicine article.

 
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From the Twittersphere...
              
    Logo     
              
              
    HIV & COVID-19     
              

              
    PrEP

Speaking of EHE...
In 2019 the CFAR received two administative supplements for EHE projects. Sophia Hussen is the project director for Exploring HIV and Mental Health Care Integration for Young Black MSM and Jessica Sales and Anandi Sheth are the project directors for Reducing HIV Among Women Living in Atlanta.

    
 
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Bulletin Board...
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Post-doctoral Fellow Sought: HIV/SIV Persistence and Cure
The Chahroudi laboratory in the Department of Pediatrics at the School of Medicine is seeking a highly motivated Postdoctoral Research Fellow to lead an NIH-funded project investigating simian immunodeficiency virus persistence in rhesus macaques. The goal of this work is to investigate HIV/SIV cure strategies to reduce the persistent viral reservoir in the setting of postnatal breast milk transmission in an infant nonhuman primate model.


Qualifications: Interested candidates must have a Ph.D. and/or an M.D. and have less than three years of postdoctoral experience. Applications should have a strong background in the immunology or virology of HIV/SIV infection. Excellent oral and written communication skills are required as is the ability to work as part of a team and with collaborators. Experience working with nonhuman primates and flow cytometry is preferred. Salary will be commensurate with experience and will follow the NIH guidelines.

To apply: please send a cover letter, CV, and contact information for three references to:
• Dr. Ann Chahroudi: achahro@emory.edu

 
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Mentoring Moment... Emory IRB COVID-19 Ramp Up Guidance

    
     Mentoring Moment...     
              

From Jessica Blackburn (Emory IRB):
Please read the new IRB COVID-19 Ramp-Up Guidance. It is also available through the COVID-19 Guidance page of the IRB website!

• This document includes a COVID-19 screening checklist and the Emory IRB's expectations for resuming in-person study visits.

• Note that Emory University has a training requirement before individuals can return to campus for any reason.

• You must follow the Emory IRB guidelines or whichever policy is more stringent for your research site.

• The guidance explains when a Modification may be needed to resume in-person visits, and when it is not.

There may be updates to the guidance as we learn more- updates will be made to the document on the website.

If you previously logged an eIRB comment noting a temporary hold due to COVID-19, please log another comment to document that you will be resuming activities.

Additionally, the IRB will host a webinar on Thursday, 6/11 at 12:00 pm to present the latest IRB COVID-19 Ramp-Up Guidance. The presentation will last approximately 40 minutes, including a moderated question and answer session. You can find a link to the live webinar, as well as recordings of past webinars on our Webinars page of the IRB website.

Best,
Jessica

 
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In Case You Missed It...
     ICYMI    
FB Live 06/02/20
 
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Research

Funding Opps

NIH FUNDING:
Standard AIDS Deadlines

No New Listings


NIH FUNDING:
Other Deadlines

No New Listings


See previously advertised Funding Opportunities in Network News archived issues.

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Recent Pubs
that link to the CFAR grant
(P30 AI050409)

32393800
Arunachalam PS, Charles TP, Joag V, Bollimpelli VS, Scott MKD, Wimmers F, Burton SL, Labranche CC, Petitdemange C, Gangadhara S, Styles TM, Quarnstrom CF, Walter KA, Ketas TJ, Legere T, Jagadeesh Reddy PB, Kasturi SP, Tsai A, Yeung BZ, Gupta S, Tomai M, Vasilakos J, Shaw GM, Kang CY, Moore JP, Subramaniam S, Khatri P, Montefiori D, Kozlowski PA, Derdeyn CA, Hunter E, Masopust D, Amara RR, Pulendran B. T cell-inducing vaccine durably prevents mucosal SHIV infection even with lower neutralizing antibody titers.
Nat Med. 2020 May 11. doi: 10.1038/s41591-020-0858-8. Online ahead of print.


31948340
Malama K, Sagaon-Teyssier L, Parker R, Tichacek A, Sharkey T, Kilembe W, Inambao M, Price MA, Spire B, Allen S. Factors associated with alcohol use before sex among HIV-negative female sex workers in Zambia. Malama K, Sagaon-Teys.
Int J STD AIDS. 2020 Feb;31(2):119-126. doi:10.1177/0956462419886159. Epub 2020 Jan 16. No abstract available.


31852329
Lipscomb J, Switchenko JM, Flowers CR, Gillespie TW, Wortley PM, Bayakly AR, Almon L, Fernando R, Ward KC. Biologic, clinical, and sociodemographic predictors of multi-agent systemic therapy for non-Hodgkin lymphoma in people living with HIV: a population-based investigation in the state of Georgia.
Leuk Lymphoma. 2020 Apr;61(4):896-904. doi: 10.1080/10428194.2019.1702176. Epub 2019 Dec 18.

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    Calendar Upcoming Events

June 4
8:00 am
ID Seminar
A marathon and a sprint: An ID fellow's journey through the worlds of XDR/MDR TB and COVID-19
Starring: Lauren Collins
Zoom Link

June 5
9:00 - 3:30
Conference
Don't be a Backseat Driver! Lead the Way Toward an End to AIDS in the South
Hosted by: Georgia and North Florida AETCs
More Information
Registration

June 5
4:00pm
Online Solidarity Vigil
To mourn victims of racist violence
Registration

June 9 (Weekly on Tuesdays)
2:00
In-Tune
Practice Mindfulness by Reflecting on Music
Open to novice and expert practitioners of mindfulness
• Questions: Catherine Aniezue (catherine.ifunanya.aniezue@emory.edu)
Zoom Link

June 10
9:00am
Webcast
Dyslipidemia Management in People with HIV
Hosted by: Tennessee AETC
More Information
Registration

June 10
12:00
Case Conference
PrEP from a Primary care perspective
Hosted by: South Carolina HIV PrEP Initiative (SCHPI)
More Information
Registration

Calendar Farther Down the Road

June 12
9:00 - Noon
Pediatric Research Webinar
COVID-19
Starring:
    Peter Hotez (Baylor)
    Evan Anderson
    Stefan Sarafianos
Register to Attend
Add to Calendar
Flyer

June 13
9:00pm - 10:00pm
Stand Up Comedy
SCIENCE RIOT ATLANTA
Register to Watch

June 15-16
Virtual Keystone
Vaccinology in the Age of Pandemics: Strategies Against COVID-19 & Other Global Threats
More Information

August 4
Symposium
Annual Pediatric Research and Career Development
Keynote: Ann Chahroudi
More Information

November 1-4
Conference
Adherence 2020
Location: Orlando
More Information

January 17-21, 2001 - New Listing
Conference
HIV Research for Prevention (HIVR4P)
Location: Cape Town and/or Online
More Information

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The Network News is a periodic email, detailing HIV/AIDS related events, funding opportunities, and achievements of CFAR members. If you have items that you wish to have included, please send them to us at cfar@emory.edu by Friday of each week. Please put "The Network News" in the subject line.

The Network News is distributed to CFAR members and fans by email every Wednesday. Except when it isn't.

Editor, Kimbi Sessions Hagen, EdD

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